Discover the development and evaluation of an oral vaccine against vibriosis, a major bacterial threat to marine aquaculture. With rising global fish demand, effective and sustainable disease management is essential to tackle disease outbreaks. This book provides a comprehensive data on vaccine formulation, quality assessment, antibody response, and gene expression work. Trials conducted in both laboratory settings and Malaysian cage farms demonstrate the vaccine’s efficacy, offering a sustainable alternative to antibiotic use. By highlighting oral vaccination as a practical disease control strategy, this essential guide offers researchers, industry professionals, and policymakers innovative solutions to improve fish health and strengthen aquaculture sustainability.